Biology Driven By Data
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- Parent Category: Biology
- Category: Cell & Molecular
Newly tenured biological engineer Ernest Fraenkel goes where the numbers lead.
Cells are incredibly complicated machines with thousands of interacting parts — and disruptions to any of those interactions can cause disease.
Tracing those connections to seek the root cause of disease is a daunting task, but it is one that MIT biological engineer Ernest Fraenkel relishes. His lab takes a systematic approach to the problem: By comparing datasets that include thousands of events inside healthy and diseased cells, they can try to figure out what has gone awry in cells that are not functioning properly.
“The central challenge of this field is how you take all those different kinds of data to get a coherent picture of what’s going on in a cell, what is wrong in a diseased cell, and how you might fix it,” says Fraenkel, an associate professor of biological engineering.
James Arthur Awarded 2015 Wolf Prize in Mathematics
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- Parent Category: Mathematics
- Category: News
James Arthur, University of Toronto (Canada), is the winner of the 2015 Wolf Prize in Mathematics
"For his monumental work on the trace formula and his fundamental contributions to the theory of automorphic representations of reductive groups." The citation states that "Arthur's ideas, achievements and the techniques he introduced will have many more deep applications in the theory of automorphic representations, and the study of locally symmetric spaces. Arthur's work is a mathematical landmark that will inspire future generations of mathematicians."
Read more: James Arthur Awarded 2015 Wolf Prize in Mathematics
Chasing down an immune protein in the brain could shed light on autism
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- Parent Category: Microbiology
- Category: Research
Fifteen years ago, the proteins that Princeton neuroscientist Lisa Boulanger has staked her career on weren't even thought to exist in the brain. Known as major histocompatibility complex class I, or MHCI proteins, they are essential for an adaptive immune response. The thought at the time was that the brain was an area of the body where the immune system wasn't active. It simply wouldn't need MHCs.
Read more: Chasing down an immune protein in the brain could shed light on autism
Emergent Properties of Quantum Materials
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- Parent Category: Nanotechnology
- Category: News
The Quantum Materials program at SIMES addresses outstanding questions in the field of Condensed Matter and Materials Physics (CMMP) related to the collective behavior of strongly correlated and magnetic materials. Largely stimulated by the discoveries of new forms of order and rich phenomena in correlated materials, these questions are at the heart of the Basic Energy Science grand challenge to understand the emergence of collective phenomena.
Emergence: Strange Behavior
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